we are clay explanation…..^^
Scleroderma can occur in families that have a tendency or a history of this disease, but in many cases also occur in families known to have no tendency to this disease. Just knowledge, Scleroderma is not considered contagious, but can greatly affect the activities of sufferers.
Basically Scleroderma is a result of overproduction and accumulation of collagen in body tissues. Collagen is a fibrous protein that forms connective tissue of your body, including skin. Although doctors are not sure what prompted the production of this abnormal collagen, the immune system seems to play a role. For unknown reasons, the immune system turns against the body, producing inflammation and excessive collagen.
Scleroderma Symptoms vary depending on the organ system involved. Diagnosis can be difficult because some early symptoms are common in the general population, and not always associated with scleroderma. The signs and symptoms of Scleroderma most common include:
* Raynaud’s phenomenon. Overreaction to cold temperatures or emotional stress, this condition constricts the small blood vessels in the hands and legs and cause numbness, pain or discoloration of fingers or toes.
* Gastroesophageal reflux disease (GERD). In addition to acid reflux, which can damage the esophagus nearest the stomach, may also have problems if your bowel muscles do not absorb nutrients properly move food through the intestines.
* Changes in skin. These changes may include swollen fingers and hands; patches of thickening of the skin, especially on the fingers and tight skin around the hands, face or mouth. The skin may appear shiny because it’s so tight, and the movement of the affected area can be limited.
Scleroderma can not be cured – there is no medicine that can stop the excessive collagen production. However, various local scleroderma sometimes heal itself. And various medications can help control symptoms or help prevent the complications of scleroderma.